| Day | Date | Opponent | Location | TV | |
| Sat | 11/06/2004 | Black and Gold Blowout presented by Mediacom | Iowa City, IA (Exhibition) | | W, 69-62
Box Score | Gametracker |
| Wed | 11/10/2004 | The Miracle Game versus Upper Iowa presented by UIHC | Iowa City, IA (Exhibition) | | W, 84-43
Recap | Box Score | Gametracker |
| Sun | 11/14/2004 | Laval University of Canada | Iowa City, IA (Exhibition) | | W, 85-77
Recap | Box Score | Gametracker |
| Fri | 11/19/2004 | Western Illinois | Iowa City, IA | ESPN Plus | W, 85-62
Recap | Box Score | Photo Gallery | Gametracker |
| Mon | 11/22/2004 | Louisville | Maui, HI (EA Sports Maui Invitational) | ESPN2 | W, 76-71
Recap | Box Score |
| Tue | 11/23/2004 | Texas | Maui, HI (EA Sports Maui Invitational) | ESPN/2 | W, 82-80
Recap | Complete Results |
| Wed | 11/24/2004 | North Carolina | Maui, HI (EA Sports Maui Invitational) | ESPN/2 | L, 106-92
Recap | Final Stats |
| Tue | 11/30/2004 | Drake | Des Moines, IA | | W, 91-75
Recap | Final Stats |
| Fri | 12/03/2004 | Centenary College | Iowa City, IA (Gazette Hawkeye Challenge) | ESPN-P | W, 88-53
Recap | Box Score | Photo Gallery |
| Sat | 12/04/2004 | UNC-Greensboro | Iowa City, IA (Gazette Hawkeye Challenge) | ESPN-P | W, 83-58
Recap | Final Stats | Photo Gallery |
| Tue | 12/07/2004 | Northern Iowa | Iowa City, IA | ESPN Plus | W, 76-73
Recap | Box Score | Photo Gallery | Gametracker |
| Fri | 12/10/2004 | Iowa State | Iowa City, IA (Hy-Vee Cy-Hawk Series) | | W, 70-63
Recap | Box Score | Gametracker |
| Sat | 12/18/2004 | Western Carolina | Iowa City, IA | | W, 88-75
Recap | Box Score | Gametracker |
| Tue | 12/21/2004 | Texas Tech | Chicago, IL | ESPN2 | W, 83-53
Recap | Box Score | Photo Gallery |
| Tue | 12/28/2004 | Air Force | Iowa City, IA | ESPN Plus | W, 73-63
Recap | Box Score | Gametracker |
| Fri | 12/31/2004 | Saint Louis | Iowa City, IA | ESPN Plus | W, 67-58
Recap | Box Score | Photo Gallery | Gametracker |
| Wed | 01/05/2005 | Michigan | Iowa City, IA | ESPN Plus | L, 65-63
Recap | Box Score | Gametracker |
| Sat | 01/08/2005 | Ohio State | Columbus, OH | ESPN-WP | L, 81-69
Recap | Box Score | Gametracker |
| Sat | 01/15/2005 | Minnesota | Iowa City, IA | ESPN-WP | W, 66-60
Recap | Box Score | Gametracker |
| Thu | 01/20/2005 | Illinois | Champaign, IL | ESPN | L, 73-68 (OT)
Recap | Box Score | Gametracker |
| Sat | 01/22/2005 | Purdue | Iowa City, IA | ESPN-WP | W, 71-57
Recap | Box Score | Photo Gallery | Gametracker |
| Wed | 01/26/2005 | Northwestern | Evanston, IL | ESPN Plus | L, 75-74 (OT)
Recap | Final Stats | Gametracker |
| Sat | 01/29/2005 | Indiana | Iowa City, IA | ESPN | W, 72-57
Recap | Box Score | Gametracker |
| Sat | 02/05/2005 | Michigan St | Iowa City, IA | ESPN-WP | L, 75-64
Recap | Box Score | Gametracker |
| Wed | 02/09/2005 | Wisconsin | Madison, WI | ESPN Plus | L, 72-69
Recap | Final Stats |
| Sat | 02/12/2005 | Northwestern | Iowa City, IA | ESPN Plus | W, 64-54
Recap | Box Score | Photo Gallery | Gametracker |
| Wed | 02/16/2005 | Purdue | West Lafayette, IN | ESPN Plus | L, 66-63
Recap | Final Stats | Gametracker |
| Sat | 02/19/2005 | Illinois | Iowa City, IA | ESPN/ESPN Plus | L, 75-65
Recap | Box Score | Photo Gallery | Gametracker |
| Wed | 02/23/2005 | Minnesota | Minneapolis, MN | ESPN Plus | L, 65-57
Recap | Final Stats | Livestats |
| Sat | 02/26/2005 | Penn St | State College, PA | ESPN-WP | W, 78-56
Recap | Final Stats | Gametracker |
| Wed | 03/02/2005 | Ohio St | Iowa City, IA | ESPN Plus | W, 74-72
Recap | Box Score | Photo Gallery | Gametracker |
| Sat | 03/05/2005 | Michigan | Ann Arbor, MI | ESPN-WP | W, 74-72 (OT)
Recap | Final Stats | Gametracker |
| Thu | 03/10/2005 | Purdue | Chicago, IL (Big Ten Tournament) | ESPN | W, 71-52
Recap | Final Stats | Gametracker |
| Fri | 03/11/2005 | Michigan State | Chicago, IL (Big Ten Tournament) | ESPN Plus | W, 71-69
Recap | Final Stats | Photo Gallery | Gametracker |
| Sat | 03/12/2005 | Wisconsin | Chicago, IL (Big Ten Tournament) | CBS | L, 59-56
Recap | Final Stats | Gametracker |
| Thu | 03/17/2005 | Cincinnati (NCAA First Round) | Indianapolis, IN | | L, 76-64
Recap | Final Stats | Gametracker |
